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Top Los Osos hotels

Back Bay Inn
Awesome location! Beautiful views of sunset. Rooms are comfortable and quiet.
Reviewed on Dec 24, 2025

Quality Suites Downtown San Luis Obispo
Great breakfast, happy hour and spacious rooms. The only issue was that you can hear every step on the floor above you and the people above us were walking a marathon.
Reviewed on Dec 31, 2025

Madonna Inn
Beautiful clean room, courteous staff. Long pool hours
Reviewed on Jan 5, 2026

Shore Cliff Hotel
Great
Reviewed on Dec 30, 2025

SeaCrest OceanFront Hotel
Breakfast had so many options. The staff was very friendly and the room was spotless. The best part was the ocean view and the stair access to the beach.
Reviewed on Jan 3, 2026

Cottage Inn By The Sea
Staff fine Sink clogged
Reviewed on Dec 29, 2025

Apple Farm
The entire area was spotless. Very clean. Give it a 20 and that still is not good enough.
Reviewed on Dec 27, 2025

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
YES
Reviewed on Jan 6, 2026

Oxford Suites Pismo Beach
Loved it!
Reviewed on Dec 31, 2025
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Los Osos Hotel & Travel Guide\n
If you're not sure how to begin planning your San Luis Obispo trip, rest assured, because there's no end of perfect accommodation options in Los Osos. Thanks to our handy accommodation guide, you can explore 30 rooms within 6 miles (10 kilometers) of Los Osos's downtown region.
The Sea Pines is a great option for your stay because it is one of the most ideally located options, one of only a small number of choices that are within walking distance of the Los Osos central area.
The Dolphin Bay Resort And Spa is approximately 12 miles (19 kilometers) outside of the center of Los Osos. Another alternative is the Avila La Fonda Hotel, which is situated 9 miles (15 kilometers) away. Other possible hotel options are the Avila Lighthouse Suites and the San Luis Bay Inn.
Should you have the time, you could travel to other parts of the Central California region. Photograph the scenery of Central California's valleys and rolling hills. You could also wind your way through many of the area's lighthouses. In this corner of United States of America adventurous visitors might also try their hand at snowboarding, skiing and mountain biking.
14 miles (22 kilometers) away from Los Osos, you'll reach Pismo Beach, where you can spend the day visiting Pismo Beach Pier and Monarch Butterfly Grove. If you'd like to spend a few nights in Pismo Beach, check out the Sandcastle Inn and Pismo Lighthouse Suites. 9 miles (15 kilometers) to the southeast of Los Osos, is Avila Beach, which is home to the Avila Village Inn and Inn At Avila Beach. If you visit Avila Beach, keep a day to explore the Avila Beach Golf Resort and Central Coast Aquarium.
Get yourself a serving of local sport with a journey to Alex G. Spanos Stadium, which is 9 miles (15 kilometers) to the east of Los Osos. Wise travelers that want to book Travelocity-listed accommodation nearby can choose from the Madonna Inn or the Granada Hotel & Bistro.
San Luis Obispo County Regional Airport is located 11 miles (18 kilometers) outside Los Osos's town center. Modern visitors who desire to find accommodation in the area can find a night at the Courtyard by Marriott San Luis Obispo or Embassy Suites by Hilton San Luis Obispo.
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Madonna Inn
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